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Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-acrylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain

✍ Scribed by Wu, Yong-Jin; Conway, Charles M.; Sun, Li-Qiang; Machet, Frederic; Chen, Jie; Chen, Ping; He, Huan; Bourin, Clotilde; Calandra, Vincenzo; Polino, Joseph L.; Davis, Carl D.; Heman, Karen; Gribkoff, Valentin K.; Boissard, Christopher G.; Knox, Ronald J.; Thompson, Mark W.; Fitzpatrick, William; Weaver, David; Harden, David G.; Natale, Joanne; Dworetzky, Steven I.; Starrett, John E.

Book ID: 123073856
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 834 KB
Volume: 23
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2013.08.092

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