✦ LIBER ✦

Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A

✍ Scribed by DeGoey, David A.; Betebenner, David A.; Grampovnik, David J.; Liu, Dachun; Pratt, John K.; Tufano, Michael D.; He, Wenping; Krishnan, Preethi; Pilot-Matias, Tami J.; Marsh, Kennan C.; Molla, Akhteruzzaman; Kempf, Dale J.; Maring, Clarence J.

Book ID: 120937400
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 350 KB
Volume: 23
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2013.04.009

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of Thienoimidazole-Based HCV N

Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors

✍ Giroux, Simon; Xu, Jinwang; Reddy, T. Jagadeeswar; Morris, Mark; Cottrell, Kevin 📂 Article 📅 2013 🏛 American Chemical Society 🌐 English ⚖ 825 KB

Discovery and in vitro Evaluation of Pot

Discovery and in vitro Evaluation of Potent Kinase Inhibitors: Pyrido[1′,2′:1,5]pyrazolo[3,4-d]pyrimidines.

✍ Michael J. Alberti; Elizabeth P. Auten; Karen E. Lackey; Octerloney B. McDonald; 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 21 KB 👁 1 views

Discovery of ABT-267, a Pan-Genotypic In

Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A

✍ DeGoey, David A.; Randolph, John T.; Liu, Dachun; Pratt, John; Hutchins, Charles 📂 Article 📅 2014 🏛 American Chemical Society 🌐 English ⚖ 606 KB

Pyrido[2,3-d]dipyrimidines 8. Synthesis

Pyrido[2,3-d]dipyrimidines 8. Synthesis of pyrrolo(2′,3′∶4,5)pyrido[2,3-d]pyrimidines

✍ I. D. Bystryakova; N. M. Smirnova; T. S. Safonova 📂 Article 📅 1993 🏛 Springer US 🌐 English ⚖ 308 KB

Pyrido[2,3-d]pyrimidines. 1. Acylation o

Pyrido[2,3-d]pyrimidines. 1. Acylation of 2,4,5-trioxo-7-amino-8H-pyrido [2,3-d]pyrimidines

✍ O. A. Burova; N. M. Smirnova; T. S. Safonova 📂 Article 📅 1990 🏛 Springer US 🌐 English ⚖ 273 KB

Ring closure reactions of pyrido[2,3-d]p

Ring closure reactions of pyrido[2,3-d]pyrimidines to pyrano[2′,3′:4,5]- and oxazolo[5′,4′:4,5]pyrido[2,3-d]pyrimidines

✍ Dang Van Tinh; Wolfgang Stadlbauer 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 419 KB

## Abstract magnified image The cyclocondensation of 5‐hydroxy‐pyrido[2,3‐__d__]pyrimidines **1** with malonates gives pyrano[2′,3′:4,5]‐pyrido[2,3‐__d__]pyrimidines **2**. Nitration of **1** and reduction with zinc in the presence of carboxylic acids/anhydrides gave 2‐alkyloxazolo[5′,4′:4,5]pyrid