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Discovery of Novel and Long Acting Muscarinic Acetylcholine Receptor Antagonists

โœ Scribed by Jin, Jian; Wang, Yonghui; Shi, Dongchuan; Wang, Feng; Davis, Roderick S.; Jin, Qi; Fu, Wei; Foley, James J.; Webb, Edward F.; Dehaas, Chris J.; Berlanga, Manuela; Burman, Miriam; Sarau, Henry M.; Morrow, Dwight M.; Rao, Parvathi; Kallal, Lorena A.; Moore, Michael L.; Rivero, Ralph A.; Palovich, Michael; Salmon, Michael; Belmonte, Kristen E.; Busch-Petersen, Jakob


Book ID
127284035
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
355 KB
Volume
51
Category
Article
ISSN
0022-2623

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๐Ÿ“œ SIMILAR VOLUMES


Molecular connectivity study of muscarin
โœ Lemont B. Kier; Lowell H. Hall ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 539 KB

A correlation between three molecular connectivity indexes and the muscarinic receptor affinity of 104 acetylcholine antagonists was found. Analysis of structure from these indexes reveals not only the importance of the onium and the bulky portions of the molecule but also their virtual independence