Discovery of Novel and Long Acting Muscarinic Acetylcholine Receptor Antagonists
โ Scribed by Jin, Jian; Wang, Yonghui; Shi, Dongchuan; Wang, Feng; Davis, Roderick S.; Jin, Qi; Fu, Wei; Foley, James J.; Webb, Edward F.; Dehaas, Chris J.; Berlanga, Manuela; Burman, Miriam; Sarau, Henry M.; Morrow, Dwight M.; Rao, Parvathi; Kallal, Lorena A.; Moore, Michael L.; Rivero, Ralph A.; Palovich, Michael; Salmon, Michael; Belmonte, Kristen E.; Busch-Petersen, Jakob
- Book ID
- 127284035
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 355 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A correlation between three molecular connectivity indexes and the muscarinic receptor affinity of 104 acetylcholine antagonists was found. Analysis of structure from these indexes reveals not only the importance of the onium and the bulky portions of the molecule but also their virtual independence