Discovery of N-(2-Aryl-cyclohexyl) Substituted Spiropiperidines as a Novel Class of GlyT1 Inhibitors.

Discovery of N-(2-Hydroxy-2-aryl-cyclohe

Discovery of N-(2-Hydroxy-2-aryl-cyclohexyl) Substituted Spiropiperidine as GlyT1 Antagonists with Improved Pharmacological Profile.

✍ Simona M. Ceccarelli; Emmanuel Pinard; Henri Stalder; Daniela Alberati 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 24 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Discovery of 4-Substituted-8-(2-hydroxy-

Discovery of 4-Substituted-8-(2-hydroxy-2-phenyl-cyclohexyl)-2,8-diaza-spiro [4.5]decan-1-one as a Novel Class of Highly Selective GlyT1 Inhibitors with Improved Metabolic Stability.

✍ Daniela Alberati; Dominik Hainzl; Synese Jolidon; Eva A. Krafft; Anke Kurt; Axel 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 19 KB 👁 1 views

4-Substituted-8-(1-phenyl-cyclohexyl)-2,

4-Substituted-8-(1-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a Novel Class of Highly Selective GlyT1 Inhibitors with Superior Pharmacological and Pharmacokinetic Parameters.

✍ Daniela Alberati; Dominik Hainzl; Synese Jolidon; Anke Kurt; Emmanuel Pinard; An 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 17 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

ChemInform Abstract: Discovery of a Nove

ChemInform Abstract: Discovery of a Novel Class of 2-Aminopyrimidines as CDK1 and CDK2 Inhibitors.

✍ Jinho Lee; Kyoung-Hee Kim; Shinwu Jeong 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

Discovery of 4-Benzylamino-Substituted α

Discovery of 4-Benzylamino-Substituted α-Carbolines as a Novel Class of Receptor Tyrosine Kinase Inhibitors

✍ Dr. Martin Krug; Dr. Kanin Wichapong; German Erlenkamp; Prof. Dr. Wolfgang Sippl 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 413 KB

Design and Synthesis of 4-Substituted-8-

Design and Synthesis of 4-Substituted-8-(2-phenyl-cyclohexyl)-2,8-diaza-spiro[4,5]decan-1-one as a Novel Class of GlyT1 Inhibitors: Achieving Selectivity Against the μ Opioid and Nociceptin/Orphanin FQ Peptide (NOP) Receptors.

✍ Andrew W. Thomas; et al. et al. 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 18 KB 👁 1 views