Discovery of Inhibitors of Cell Adhesion Molecule Expression in Human Endothelial Cells. 1. Selective Inhibition of ICAM-1 and E-Selectin Expression
โ Scribed by Stewart, Andrew O.; Bhatia, Pramila A.; McCarty, Catherine M.; Patel, Meena V.; Staeger, Michael A.; Arendsen, David L.; Gunawardana, Indrani W.; Melcher, Laura M.; Zhu, Gui-Dong; Boyd, Steven A.; Fry, Dennis G.; Cool, Barbara L.; Kifle, Lemma; Lartey, Kraig; Marsh, Kennan C.; Kempf-Grote, Anita J.; Kilgannon, Patrick; Wisdom, Wendy; Meyer, Joey; Gallatin, W. Michael; Okasinski, Gregory F.
- Book ID
- 118127052
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 354 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-2623
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๐ SIMILAR VOLUMES
Endothelial cells, as they normally exist in the vasculature as quiescent cells, perform several functions. In an inflammatory response, endothelial cells are activated to up-regulate a number of genes, including E-selectin (ELAM-l), VCAM-1, ICAM-1, interleukin (IL)-l, IL-8 and plasminogen activator