✦ LIBER ✦

Discovery of Imidazo[1,2- b ][1,2,4]triazines as GABA A α2/3 Subtype Selective Agonists for the Treatment of Anxiety

✍ Scribed by Russell, Michael G. N.; Carling, Robert W.; Street, Leslie J.; Hallett, David J.; Goodacre, Simon; Mezzogori, Elena; Reader, Michael; Cook, Susan M.; Bromidge, Frances A.; Newman, Robert; Smith, Alison J.; Wafford, Keith A.; Marshall, George R.; Reynolds, David S.; Dias, Rebecca; Ferris, Pushpindar; Stanley, Jo; Lincoln, Rachael; Tye, Spencer J.; Sheppard, Wayne F. A.; Sohal, Bindi; Pike, Andrew; Dominguez, Maria; Atack, John R.; Castro, José L.

Book ID: 121455908
Publisher: American Chemical Society
Year: 2006
Tongue: English
Weight: 129 KB
Volume: 49
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm051200u

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Imidazo[1,2-b][1,2,4]triazines as α2/α3

Imidazo[1,2-b][1,2,4]triazines as α2/α3 subtype selective GABAA agonists for the treatment of anxiety

✍ Andrew S.R. Jennings; Richard T. Lewis; Michael G.N. Russell; David J. Hallett; 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 134 KB

Imidazo[1,2-a]pyrazin-8-ones, Imidazo[1,

Imidazo[1,2-a]pyrazin-8-ones, Imidazo[1,2-d][1,2,4]triazin-8-ones and Imidazo[2,1-f][1,2,4]triazine-8-ones as α2/α3 Subtype Selective GABAA Agonists for the Treatment of Anxiety.

✍ Simon C. Goodacre; David J. Hallett; Robert W. Carling; Jose L. Castro; David S. 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 19 KB 👁 1 views

Palladium-Catalyzed Regioselective Aryla

Palladium-Catalyzed Regioselective Arylation of Imidazo[1,2- b ][1,2,4]triazine: Synthesis of an α 2/3 -Selective GABA Agonist

✍ Gauthier,, Donald R.; Limanto, John; Devine, Paul N.; Desmond, Richard A.; Szumi 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 177 KB

A Pyridazine Series of α2/α3 Subtype Sel

A Pyridazine Series of α2/α3 Subtype Selective GABA A Agonists for the Treatment of Anxiety

✍ Lewis, Richard T.; Blackaby, Wesley P.; Blackburn, Timothy; Jennings, Andrew S. 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 328 KB

Imidazo[1,2 -a ]pyrimidines as Functiona

Imidazo[1,2 -a ]pyrimidines as Functionally Selective and Orally Bioavailable GABA A α2/α3 Binding Site Agonists for the Treatment of Anxiety Disorders

✍ Goodacre, Simon C.; Street, Leslie J.; Hallett, David J.; Crawforth, James M.; K 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 129 KB

2-(Anilinomethyl)imidazolines as α 1 Adr

2-(Anilinomethyl)imidazolines as α 1 Adrenergic Receptor Agonists: the Discovery of α 1a Subtype Selective 2‘-Alkylsulfonyl-Substituted Analogues

✍ Hodson, Stephen J.; Bishop, Michael J.; Speake, Jason D.; Navas, Frank; Garrison 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 116 KB