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Discovery of HIV-1 Integrase Inhibitors: Pharmacophore Mapping, Virtual Screening, Molecular Docking, Synthesis, and Biological Evaluation

✍ Scribed by Bhatt, Hardik; Patel, Paresh; Pannecouque, Christophe


Book ID
120839064
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
614 KB
Volume
83
Category
Article
ISSN
1747-0277

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## Abstract Two sets of compounds derived from the fusion of a diversely annulated naphthoxazepinedione system with 1,3‐thiazole and 1,3‐oxazole are described. These compounds are close analogues of previously reported thiazolothiazepine inhibitors of human immunodeficiency virus typeβ€…1 integrase (