Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)

✍ Scribed by Deng, Hongfeng; O’Keefe, Heather; Davie, Christopher P.; Lind, Kenneth E.; Acharya, Raksha A.; Franklin, G. Joseph; Larkin, Jonathan; Matico, Rosalie; Neeb, Michael; Thompson, Monique M.; Lohr, Thomas; Gross, Jeffrey W.; Centrella, Paolo A.; O’Donovan, Gary K.; Bedard, Katie L. (Sargent); van Vloten, Kurt; Mataruse, Sibongile; Skinner, Steven R.; Belyanskaya, Svetlana L.; Carpenter, Tiffany Y.; Shearer, Todd W.; Clark, Matthew A.; Cuozzo, John W.; Arico-Muendel, Christopher C.; Morgan, Barry A.

• Book ID: 118160149
• Publisher: American Chemical Society
• Year: 2012
• Tongue: English
• Weight: 689 KB
• Volume: 55
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm300449x