M13 phages that display random disulfide constrained heptapeptides on their gpIII proteins were used to select for high affinity ligands to hepatitis B core antigen (HBcAg). Phages bearing the amino acid sequences C-WSFFSNI-C and C-WPFWGPW-C were isolated, and a binding assay in solution showed that
Discovery of high-affinity peptide binders to BLyS by phage display
β Scribed by Tony J. Fleming; Meena Sachdeva; Marko Delic; James Beltzer; Charles R. Wescott; Mary Devlin; Robert C. Lander; Andrew E. Nixon; Viktor Roschke; David M. Hilbert; Daniel J. Sexton
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 145 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0952-3499
- DOI
- 10.1002/jmr.722
No coin nor oath required. For personal study only.
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