✦ LIBER ✦

Discovery of GS-9256: A novel phosphinic acid derived inhibitor of the hepatitis C virus NS3/4A protease with potent clinical activity

✍ Scribed by X. Christopher Sheng; Anthony Casarez; Ruby Cai; Michael O. Clarke; Xiaowu Chen; Aesop Cho; William E. Delaney IV; Edward Doerffler; Mingzhe Ji; Michael Mertzman; Rowchanak Pakdaman; Hyung-Jung Pyun; Tanisha Rowe; Qiaoyin Wu; Jie Xu; Choung U. Kim

Book ID: 113496483
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 344 KB
Volume: 22
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2011.12.038

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Discovery of GS-925

ChemInform Abstract: Discovery of GS-9256: A Novel Phosphinic Acid Derived Inhibitor (I) of the Hepatitis C Virus NS3/4A Protease with Potent Clinical Activity.

✍ X. Christopher Sheng; et al. et al. 📂 Article 📅 2012 🏛 John Wiley and Sons ⚖ 22 KB

Discovery of novel P3-oxo inhibitor of h

Discovery of novel P3-oxo inhibitor of hepatitis C virus NS3/4A serine protease

✍ Maosheng Duan; Wieslaw Kazmierski; Renae Crosby; Margaret Gartland; Jinjing Ji; 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 783 KB

1168 BL-8030: A NOVEL, POTENT, SELECTIVE

1168 BL-8030: A NOVEL, POTENT, SELECTIVE, ORALLY AVAILABLE INHIBITOR OF HEPATITIS C VIRUS NS3/4A PROTEASE

✍ Halfon, P.; Courcambeck, J.; Whitaker, T.; Tharnish, P.M.; McBrayer, T.R.; Coats 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 53 KB

Discovery of a Potent and Selective Nonc

Discovery of a Potent and Selective Noncovalent Linear Inhibitor of the Hepatitis C Virus NS3 Protease (BI 201335)

✍ Llinàs-Brunet, Montse; Bailey, Murray D.; Goudreau, Nathalie; Bhardwaj, Punit K 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 1022 KB

Discovery of Danoprevir (ITMN-191/R7227)

Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease

✍ Jiang, Yutong; Andrews, Steven W.; Condroski, Kevin R.; Buckman, Brad; Serebryan 📂 Article 📅 2013 🏛 American Chemical Society 🌐 English ⚖ 872 KB

Discovery of MK-1220: A Macrocyclic Inhi

Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure

✍ Rudd, Michael T.; McCauley, John A.; Butcher, John W.; Romano, Joseph J.; McInty 📂 Article 📅 2011 🏛 American Chemical Society 🌐 English ⚖ 1016 KB