๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Discovery of Fused Azetidines as Novel Selective Neuronal Nicotinic Receptor (NNR) Agonists

โœ Scribed by Jianguo Ji; William H. Bunnelle; Tao Li; Jennifer M. Pace; Michael R. Schrimpf; Kevin B. Sippy; David J. Anderson; Michael D. Meyer

Book ID
101990909
Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Discovery of fused azetidines as novel s
Discovery of fused azetidines as novel selective ฮฑ4ฮฒ2 neuronal nicotinic receptor (NNR) agonists
โœ Ji, Jianguo; Bunnelle, William H.; Li, Tao; Pace, Jennifer M.; Schrimpf, Michael ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› International Union of Pure and Applied Chemistry ๐ŸŒ English โš– 201 KB

## Abstract An efficient synthesis of (1__R__,5__S__)-6-(5-cyano-3-pyridinyl)-3,6-diaza-bicyclo[3.2.0]heptane **A-366833**, a novel potent selective neuronal nicotinic receptor (NNR) agonist, is described. The enantiomerically pure pharmacophore benzyl (1__S__,5__S__)-3,6-diaza-bicyclo[3.2.0]heptan