Discovery of Further Pyrrolidine trans -Lactams as Inhibitors of Human Neutrophil Elastase (HNE) with Potential as Development Candidates and the Crystal Structure of HNE Complexed with an Inhibitor (GW475151)

✍ Scribed by Macdonald, Simon J. F.; Dowle, Michael D.; Harrison, Lee A.; Clarke, Geoffrey D. E.; Inglis, Graham G. A.; Johnson, Martin R.; Shah, Pritom; Smith, Robin A.; Amour, Augustin; Fleetwood, Gill; Humphreys, Davina C.; Molloy, Christopher R.; Dixon, Mary; Godward, Rosalind E.; Wonacott, Alan J.; Singh, Onkar M. P.; Hodgson, Simon T.; Hardy, George W.

• Book ID: 120024072
• Publisher: American Chemical Society
• Year: 2002
• Tongue: English
• Weight: 475 KB
• Volume: 45
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm020881f