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Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung and breast carcinomas

✍ Scribed by Senchenko, Vera N; Liu, Jian; Loginov, Witaly; Bazov, Igor; Angeloni, Debora; Seryogin, Yury; Ermilova, Valeria; Kazubskaya, Tatiana; Garkavtseva, Raisa; Zabarovska, Veronika I

Book ID: 110068829
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 674 KB
Volume: 23
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1207760

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## Abstract Genome scanning at a 1‐Mb resolution was undertaken in 29 lung cancer cell lines to clarify the distribution of homozygous (i.e., both allele) deletions along lung cancer genomes, using a high‐resolution single nucleotide polymorphism array. Eighteen regions, including two known tumor s