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Discovery of circulating microRNAs associated with human prostate cancer using a mouse model of disease

✍ Scribed by Luke A. Selth; Scott Townley; Joanna L. Gillis; Aleksandra M. Ochnik; Krisna Murti; Robyn J. Macfarlane; Kim N. Chi; Villis R. Marshall; Wayne D. Tilley; Lisa M. Butler


Book ID
112101581
Publisher
John Wiley and Sons
Year
2011
Tongue
French
Weight
795 KB
Volume
131
Category
Article
ISSN
0020-7136

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## Abstract ## Background Gene‐directed enzyme prodrug therapy (GDEPT) based on the __E. coli__ enzyme purine nucleoside phosphorylase (PNP) represents a new approach for treating slow growing tumours like prostate cancer (PCa). Expressed enzyme converts a systemically administered prodrug, fludar