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Discovery of Benzylidenebenzofuran-3(2 H )-one (Aurones) as Inhibitors of Tyrosinase Derived from Human Melanocytes

✍ Scribed by Okombi, Sabrina; Rival, Delphine; Bonnet, Sébastien; Mariotte, Anne-Marie; Perrier, Eric; Boumendjel, Ahcène


Book ID
120395808
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
68 KB
Volume
49
Category
Article
ISSN
0022-2623

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Synthesis of 2H-benzo[b][1,4]oxazin-3(4H
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Novel 2H-benzo[b][1,4]oxazin-3(4H)-ones have been synthesized by condensation, reduction, O-alkylation and Smiles rearrangement using 3-bromo-4-hydroxy benzaldehyde, anilines, and chloroacetyl chloride as starting materials. All the synthesized compounds have been characterized by (1)H NMR, (13)C NM