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Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI)

✍ Scribed by Miller, William H.; Seefeld, Mark A.; Newlander, Kenneth A.; Uzinskas, Irene N.; Burgess, Walter J.; Heerding, Dirk A.; Yuan, Catherine C. K.; Head, Martha S.; Payne, David J.; Rittenhouse, Stephen F.; Moore, Terrance D.; Pearson, Stewart C.; Berry, Valerie; DeWolf, Walter E.; Keller, Paul M.; Polizzi, Brian J.; Qiu, Xiayang; Janson, Cheryl A.; Huffman, William F.


Book ID
119978904
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
181 KB
Volume
45
Category
Article
ISSN
0022-2623

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Benzothiophene carboxamide derivatives a
✍ Tanushree Banerjee; Shailendra Kumar Sharma; Neha Kapoor; Vishnu Dwivedi; Namita πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 419 KB

## Abstract Benzothiophene derivatives like benzothiophene sulphonamides, biphenyls, or carboxyls have been synthesized and have found wide pharmacological usage. Here we report, bromo‐benzothiophene carboxamide derivatives as potent, slow tight binding inhibitors of __Plasmodium__ enoyl‐acyl carri