✦ LIBER ✦

Discovery of a Rhodanine Class of Compounds as Inhibitors of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase

✍ Scribed by Kumar, Gyanendra; Parasuraman, Prasanna; Sharma, Shailendra Kumar; Banerjee, Tanushree; Karmodiya, Krishanpal; Surolia, Namita; Surolia, Avadhesha

Book ID: 111943122
Publisher: American Chemical Society
Year: 2007
Tongue: English
Weight: 369 KB
Volume: 50
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm061257w

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

SAR and pharmacophore models for the rho

SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase

✍ Gyanendra Kumar; Tanushree Banerjee; Neha Kapoor; Namita Surolia; Avadhesha Suro 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 418 KB

## Abstract Significance of type II fatty acid synthase pathway in the life cycle of malarial parasite has long been established. Enoyl acyl carrier protein (ACP) reductase of __Plasmodium falciparum__ (PfENR) is the rate determining enzyme of its elongation module. Hence, PfENR has been a target f

Discovery of novel inhibitors targeting

Discovery of novel inhibitors targeting enoyl–acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening

✍ George Nicola; Colin A. Smith; Edinson Lucumi; Mack R. Kuo; Luchezar Karagyozov; 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 612 KB

Pyrrolidine Carboxamides as a Novel Clas

Pyrrolidine Carboxamides as a Novel Class of Inhibitors of Enoyl Acyl Carrier Protein Reductase from Mycobacterium tuberculosis

✍ He, Xin; Alian, Akram; Stroud, Robert; Ortiz de Montellano, Paul R. 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 555 KB

Mutational analysis of the triclosan-bin

Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum

✍ KAPOOR, Mili; GOPALAKRISHNAPAI, Jayashree; SUROLIA, Namita; SUROLIA, Avadhesha 📂 Article 📅 2004 🏛 Portland Press 🌐 English ⚖ 560 KB

X-ray Structural Analysis of Plasmodium

X-ray Structural Analysis of Plasmodium falciparum Enoyl Acyl Carrier Protein Reductase as a Pathway toward the Optimization of Triclosan Antimalarial Efficacy

✍ Freundlich, J. S.; Wang, F.; Tsai, H.-C.; Kuo, M.; Shieh, H.-M.; Anderson, J. W. 📂 Article 📅 2007 🏛 The American Society for Biochemistry and Molecula 🌐 English ⚖ 479 KB

Synthesis of hydrophobicN-acylated isoni

Synthesis of hydrophobicN-acylated isonicotinic acid hydrazide derivatives as potential enoyl–acyl carrier protein reductase (InhA) inhibitors

✍ Naveen Kumar, H. S.; Parumasivam, Thaigarajan; Ibrahim, Pazilah; Asmawi, Mohd. Z 📂 Article 📅 2013 🏛 Springer-Verlag 🌐 English ⚖ 494 KB