✦ LIBER ✦

Discovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as Analgesics ∇

✍ Scribed by Boger, Dale L.; Miyauchi, Hiroshi; Du, Wu; Hardouin, Christophe; Fecik, Robert A.; Cheng, Heng; Hwang, Inkyu; Hedrick, Michael P.; Leung, Donmienne; Acevedo, Orlando; Guimarães, Cristiano R. W.; Jorgensen, William L.; Cravatt, Benjamin F.

Book ID: 120912648
Publisher: American Chemical Society
Year: 2005
Tongue: English
Weight: 303 KB
Volume: 48
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm049614v

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Potent and Selective α-Ketoheterocycle-B

Potent and Selective α-Ketoheterocycle-Based Inhibitors of the Anandamide and Oleamide Catabolizing Enzyme, Fatty Acid Amide Hydrolase

✍ Romero, F. Anthony; Du, Wu; Hwang, Inkyu; Rayl, Thomas J.; Kimball, F. Scott; Le 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 255 KB

Discovery of Boronic Acids as Novel and

Discovery of Boronic Acids as Novel and Potent Inhibitors of Fatty Acid Amide Hydrolase

✍ Minkkilä, Anna; Saario, Susanna M.; Käsnänen, Heikki; Leppänen, Jukka; Poso, 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 129 KB

Discovery of an Exceptionally Potent and

Discovery of an Exceptionally Potent and Selective Class of Fatty Acid Amide Hydrolase Inhibitors Enlisting Proteome-Wide Selectivity Screening: Concurrent Optimization of Enzyme Inhibitor Potency and Selectivity.

✍ Donmienne Leung; Wu Du; Christophe Hardouin; Heng Cheng; Inkyu Hwang; Benjamin F 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 14 KB

Synthesis and Evaluation of Benzothiazol

Synthesis and Evaluation of Benzothiazole-Based Analogues as Novel, Potent, and Selective Fatty Acid Amide Hydrolase Inhibitors

✍ Wang, Xueqing; Sarris, Katerina; Kage, Karen; Zhang, Di; Brown, Scott P.; Kolasa 📂 Article 📅 2009 🏛 American Chemical Society 🌐 English ⚖ 1017 KB

Discovery of α,γ-Diketo Acids as Potent

Discovery of α,γ-Diketo Acids as Potent Selective and Reversible Inhibitors of Hepatitis C Virus NS5b RNA-Dependent RNA Polymerase

✍ Summa, Vincenzo; Petrocchi, Alessia; Pace, Paola; Matassa, Victor G.; De Frances 📂 Article 📅 2004 🏛 American Chemical Society 🌐 English ⚖ 55 KB

1-(3-Biaryloxy-2-oxopropyl)indole-5-carb

1-(3-Biaryloxy-2-oxopropyl)indole-5-carboxylic Acids and Related Compounds as Dual Inhibitors of Human Cytosolic Phospholipase A2α and Fatty Acid Amide Hydrolase

✍ Stefan Zahov; Dr. Andreas Drews; Dr. Mark Hess; Alwine Schulze Elfringhoff; Prof 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB