Discovery of a Potent, Non-Peptide Bradykinin B1 Receptor Antagonist.
β Scribed by Dai-Shi Su; et al. et al.
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 60 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The airways' pharmacology of DNK333 ((1R,3R,2E)βNβ[3,4βdichlorobenzyl)]β4β[(hexahydroβ2βoxoβ1Hβazepinβ3βyl)amino]βNβmethylβ3,5bis(trifluoromethyl) benzamide), a potent and selective dual NK~1~/NK~2~ neurokinin receptor antagonist is described in the present paper. DNK333 bound with high