Discovery of a Fluoroindolo[2,3- a ]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11 †

✍ Scribed by Saulnier, Mark G.; Balasubramanian, Balu N.; Long, Byron H.; Frennesson, David B.; Ruediger, Edward; Zimmermann, Kurt; Eummer, Jeffrey T.; St. Laurent, Denis R.; Stoffan, Karen M.; Naidu, B. Narasimhulu; Mahler, Mikael; Beaulieu, Francis; Bachand, Carol; Lee, Frank Y.; Fairchild, Craig R.; Stadnick, Linda K.; Rose, William C.; Solomon, Carola; Wong, Henry; Martel, Alain; Wright, John J.; Kramer, Robert; Langley, David R.; Vyas, Dolatrai M.

• Book ID: 121219314
• Publisher: American Chemical Society
• Year: 2005
• Tongue: English
• Weight: 136 KB
• Volume: 48
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm049090z