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Discovery of a Biologically Active Thiostrepton Fragment

✍ Scribed by Nicolaou, K. C.; Zak, Mark; Rahimipour, Shai; Estrada, Anthony A.; Lee, Sang Hyup; O'Brate, Aurora; Giannakakou, Paraskevi; Ghadiri, M. Reza


Book ID
127085379
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
85 KB
Volume
127
Category
Article
ISSN
0002-7863

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Solution synthesis of a biologically act
✍ Kalbacher, Hubert ;Jahan, Meeno ;MiheliΔ‡, Mirna ;Zaman, Fakhar ;Voelter, Wolfgan πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 423 KB

## Abstract The C‐terminal fragment 33–41 of thymosin Ξ²~9~ is synthesized by solution synthesis, using the strategy of maximum side‐chain protection with acid‐labile __tert__‐butyl groups and temporary __N__^Ξ±^‐benzyloxycarbonyl protection during the elongation steps. Part of this peptide is deprot