Discovery of 2-[1-(4-Chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic Acid (PSI-421), a P-Selectin Inhibitor with Improved Pharmacokinetic Properties and Oral Efficacy in Models of Vascular Injury

✍ Scribed by Huang, Adrian; Moretto, Alessandro; Janz, Kristin; Lowe, Michael; Bedard, Patricia W.; Tam, Steve; Di, Li; Clerin, Valerie; Sushkova, Natalia; Tchernychev, Boris; Tsao, Desiree H. H.; Keith, James C.; Shaw, Gray D.; Schaub, Robert G.; Wang, Qin; Kaila, Neelu

• Book ID: 118255890
• Publisher: American Chemical Society
• Year: 2010
• Tongue: English
• Weight: 98 KB
• Volume: 53
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm9013696