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Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors

✍ Scribed by Chan, Laval; Jin, Haolun; Stefanac, Tomislav; Lavallée, Jean-François; Falardeau, Guy; Wang, Wei; Bédard, Jean; May, Suzanne; Yuen, Leonard


Book ID
127387776
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
37 KB
Volume
42
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Discovery of 1,6-Na
✍ Laval Chan; Haolun Jin; Tomislav Stefanac; Jean-Francois Lavallee; Guy Falardeau 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors. -A series of 20 1,6-naphthyridines, e.g. (I), is synthesized by amidation of key intermediate (IV) and in case of its halogen analogue (V) by subsequent Stille coupling with stannanes, e.g. (V