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Discovery and X-ray Crystallographic Analysis of a Spiropiperidine Iminohydantoin Inhibitor of β-Secretase ‡

✍ Scribed by Barrow, James C.; Stauffer, Shaun R.; Rittle, Kenneth E.; Ngo, Phung L.; Yang, ZhiQiang; Selnick, Harold G.; Graham, Samuel L.; Munshi, Sanjeev; McGaughey, Georgia B.; Holloway, M. Katharine; Simon, Adam J.; Price, Eric A.; Sankaranarayanan, Sethu; Colussi, Dennis; Tugusheva, Katherine; Lai, Ming-Tain; Espeseth, Amy S.; Xu, Min; Huang, Qian; Wolfe, Abigail; Pietrak, Beth; Zuck, Paul; Levorse, Dorothy A.; Hazuda, Daria; Vacca, Joseph P.

Book ID: 120818173
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 380 KB
Volume: 51
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm800914n

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