Discovery and verification of amyotrophic lateral sclerosis biomarkers by proteomics
✍ Scribed by Henrik Ryberg; Jiyan An; Samuel Darko; Jonathan Llyle Lustgarten; Matt Jaffa; Vanathi Gopalakrishnan; David Lacomis; Merit Cudkowicz; Robert Bowser
- Book ID
- 102533100
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 335 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0148-639X
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📜 SIMILAR VOLUMES
## Abstract Biomarker discovery is a central application in today's proteomic research. There is an urgent need for valid biomarkers to improve diagnostic tools and treatment in many disorders, such as the rapidly progressing neurodegenerative disorder amyotrophic lateral sclerosis (ALS) that has a
There is an urgent need for novel biomarkers that can be used to improve the diagnosis, predict the disease progression, improve our understanding of the pathology or serve as therapeutic targets for neurodegenerative diseases. Cerebrospinal fluid (CSF) is in direct contact with the CNS and reflects