Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase †

✍ Scribed by Albrecht, Brian K.; Harmange, Jean-Christophe; Bauer, David; Berry, Loren; Bode, Christiane; Boezio, Alessandro A.; Chen, April; Choquette, Deborah; Dussault, Isabelle; Fridrich, Cary; Hirai, Satoko; Hoffman, Doug; Larrow, Jay F.; Kaplan-Lefko, Paula; Lin, Jasmine; Lohman, Julia; Long, Alexander M.; Moriguchi, Jodi; O’Connor, Anne; Potashman, Michele H.; Reese, Monica; Rex, Karen; Siegmund, Aaron; Shah, Kavita; Shimanovich, Roman; Springer, Stephanie K.; Teffera, Yohannes; Yang, Yajing; Zhang, Yihong; Bellon, Steven F.

• Book ID: 118748802
• Publisher: American Chemical Society
• Year: 2008
• Tongue: English
• Weight: 729 KB
• Volume: 51
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm800043g