✦ LIBER ✦

Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6

✍ Scribed by Ken Shimamura; Akira Nagumo; Yasuhisa Miyamoto; Hidefumi Kitazawa; Maki Kanesaka; Ryo Yoshimoto; Katsumi Aragane; Naomi Morita; Tomoyuki Ohe; Toshiyuki Takahashi; Tsuyoshi Nagase; Nagaaki Sato; Shigeru Tokita

Book ID: 113588617
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 537 KB
Volume: 630
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2009.12.033

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of a Potent, Selective, and Or

Discovery of a Potent, Selective, and Orally Active Proteasome Inhibitor for the Treatment of Cancer

✍ Dorsey, Bruce D.; Iqbal, Mohamed; Chatterjee, Sankar; Menta, Ernesto; Bernardini 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 161 KB

Discovery of L-791,943: A Potent, Select

Discovery of L-791,943: A Potent, Selective, Non-Emetic and Orally Active Phosphodiesterase-4 Inhibitor.

✍ Daniel Guay; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB

Discovery of benzoylisoindolines as a no

Discovery of benzoylisoindolines as a novel class of potent, selective and orally active GlyT1 inhibitors

✍ Emmanuel Pinard; Daniela Alberati; Markus Bender; Edilio Borroni; Virginie Brom; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 730 KB

Pharmacological characterization of the

Pharmacological characterization of the potent, selective and orally active cathepsin K inhibitor MIV-711

✍ U. Grabowska⁎; I. Henderson; M. Edlund; L. Vrang; S. Sedig; Y. Terelius; K. Wiks 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 102 KB

ChemInform Abstract: Discovery and Chara

ChemInform Abstract: Discovery and Characterization of the Potent, Selective and Orally Bioavailable MMP Inhibitor ABT-770.

✍ Michael L. Curtin; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

Discovery of novel, potent, selective, a

Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole core

✍ Dong-Ming Shen; Edward J. Brady; Mari R. Candelore; Qing Dallas-Yang; Victor D.- 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 461 KB

A novel class of 1,3,5-pyrazoles has been discovered as potent human glucagon receptor antagonists. Notably, compound 26 is orally bioavailable in several preclinical species and shows selectivity towards cardiac ion channels, other family B receptors such hGIP and hGLP1, and a large panel of enzyme