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Discoidin Domain Receptor-1a (DDR1a) Promotes Glioma Cell Invasion and Adhesion in Association with Matrix Metalloproteinase-2

✍ Scribed by Rosalyn Ram; Gustavo Lorente; Karoly Nikolich; Roman Urfer; Erik Foehr; Usha Nagavarapu

Book ID
106480395
Publisher
Springer US
Year
2005
Tongue
English
Weight
646 KB
Volume
76
Category
Article
ISSN
0167-594X

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## Abstract Membrane‐type metalloproteinase‐1 (MT1‐MMP) is a transmembrane metalloproteinase overexpressed in tumors, which plays a major role in the first step of pro‐MMP‐2 activation, leading to the generation of an intermediate 62 kDa species. The second step of MMP‐2 activation that yields to t