Disappearance of multiple sclerosis lesions with severely prolonged T1 on images obtained by a flair pulse sequence
✍ Scribed by Jan Hein T.M. van Waesberghe; Jonas A. Castelijns; Jan G.E. Weerts; Geert J. Lycklama àNijeholt; Joop P.M. Hillegers; Chris H. Polman; Frederik Barkhof
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 382 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0730-725X
No coin nor oath required. For personal study only.
✦ Synopsis
Although the superiority of FLAIR over conventional T,-weighted spin-echo (SE) is still unclear, one potential advantage would be its use in quantitative lesion load measurements. We have observed a potential pitfall regarding the use of FLAIR in image quantification. We report a case where a part of the hyperintense lesions on T2 SE, which was hypointense on Tl SE, subsequently was found to be isointense to brain on FLAIR images. Therefore, quantification of lesion load by means of FLAIR might underestimate the "true" lesion load, as seen on T2 SE.