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DIRECTLY LINKED SOLUBLE IL-6 RECEPTOR–IL-6 FUSION PROTEIN INDUCES ASTROCYTE DIFFERENTIATION FROM NEUROEPITHELIAL CELLS VIA ACTIVATION OF STAT3

✍ Scribed by Takumi Takizawa; Makoto Yanagisawa; Wataru Ochiai; Kiyoshi Yasukawa; Takahiko Ishiguro; Kinichi Nakashima; Tetsuya Taga

Book ID
115596640
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
496 KB
Volume
13
Category
Article
ISSN
1043-4666

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## Abstract Human T‐cell leukemia virus type‐I (HTLV‐I) encodes for the viral protein Tax, which is known to significantly disrupt transcriptional control of cytokines, cytokine receptors and other immuno‐modulatory proteins in T cells. Specific dysregulation of these factors can alter the course a