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Directed expression of Hox A3 upregulates target genes associated with wound healing in diabetic mice

✍ Scribed by Kimberly A. Mace; Scott Hansen; Nancy Boudreau; David Young

Book ID
113676035
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
52 KB
Volume
199
Category
Article
ISSN
1072-7515

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## Abstract Wound healing is impaired in elderly patients with diabetes mellitus. We hypothesized that age‐dependent impairment of cutaneous wound healing in __db__/__db__ diabetic mice: (a) would correlate with reduced expression of the transcription factor hypoxia‐inducible factor 1Ξ± (HIF‐1Ξ±) as