Directed evolution of enzyme catalysts
β Scribed by Olga Kuchner; Frances H. Arnold
- Book ID
- 114152916
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 821 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0167-7799
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Laboratory evolutionists continue to generate better enzymes for industrial and research applications. Exciting developments include new biocatalysts for enantioselective carbon-carbon bond formation and fatty acid production in plants. Creative contributions to the repertoire of evolutionary method
Directed evolution has now been used for over two decades as an alternative to rational design for protein engineering. Protein function, however, is complex, and modifying enzyme activity is a tall order. We can now improve existing enzyme activity, change enzyme selectivity and evolve function de
On the way to a combinatorial biotechnology? The directed evolution of enzymes promises a rapid access to effective biocatalysts. New molecular biology techniques for random mutagenesis in combination with high-throughput screening might revolutionize the creation of enzymes with new and improved pr