An Error-Prone T7 RNA Polymerase Mutant
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Susanne Brakmann; Sandra Grzeszik
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Article
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2001
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John Wiley and Sons
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English
⚖ 210 KB
Viruses replicate their genomes at exceptionally high mutation rates. Their offspring evolve rapidly and therefore, are able to evade common immunological and chemical antiviral agents. In parallel, virus genomes cannot tolerate a further increase in mutation rate: Experimental evidence exists that