Directed Assembly of Periodic Materials from Protein and Oligonucleotide-Modified Nanoparticle Building Blocks

✍ Scribed by So-Jung Park; Anne A. Lazarides; Chad A. Mirkin; Robert L. Letsinger

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 130 KB
• Volume: 40
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/1521-3773(20010803)40:15<2909::aid-anie2909>3.0.co;2-o

✦ Synopsis

DNA hybridization enables the three-dimensional assembly of Au nanoparticles and streptavidin. The high-density DNA-modified Au nanoparticles were stable to nonspecific binding of streptavidin. Structural and melting investigations on the assemblies showed their formation was reversible.