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Direct Visualization of Vesicle Maturation and Plasma Membrane Protein Trafficking

✍ Scribed by Douglas S. Richardson; Lois M. Mulligan

Book ID
106412765
Publisher
Springer
Year
2009
Tongue
English
Weight
235 KB
Volume
20
Category
Article
ISSN
1053-0509

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## Abstract One pathological characteristic of Alzheimer's disease (AD) is extensive synapse loss. Presenilin 1 (PS1) is linked to the pathogenesis of early onset familial Alzheimer's disease (FAD) and is localized at the synapse, where it binds N‐cadherin and modulates its adhesive activity. To el