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Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300

โœ Scribed by Yoneyama, M.

Book ID
111745839
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
495 KB
Volume
17
Category
Article
ISSN
0261-4189

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Direct triggering of the type I interfer
Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300
โœ Yoneyama, M. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 495 KB

It has been hypothesized that certain viral infections directly activate a transcription factor(s) which is responsible for the activation of genes encoding type I interferons (IFNs) and interferon-stimulated genes (ISGs) via interferon regulatory factor (IRF) motifs present in their respective prom