𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Direct synthesis of trisubstituted isothiazole 1,1-dioxides. Regioselective substitution reactions at C-3 and C-4

✍ Scribed by Britcher, Susan F.; Cochran, David W.; Phillips, Brian T.; Springer, James P.; Lumma, William C.

Book ID
120045622
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
637 KB
Volume
48
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Fused 1,2-Dithioles. Part VII : Synthesi
Fused 1,2-Dithioles. Part VII : Synthesis and Reactions of 4H-1,2-Dithiolo[4,3-c]isothiazoles
✍ Hans-Dietrich Stachel; Barbara Zimmer; Eduard Eckl; Katharina Semmlinger; Wolfga 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 German ⚖ 268 KB

## Abstract The 1,2‐dithiolosultam derivative 14 was obtained from the (__α__‐bromoalkylidene)propenesultam derivative 9 (__Scheme 1__). Regioselective cleavage of the two ester groups (→1b or 2b) allowed the preparation of derivatives with different substituents at C(3) in the dithiole ring (see 2

Properties and Reactions of Substituted
Properties and Reactions of Substituted 1,2-Thiazetidine 1,1-Dioxides: 3-Acetoxy-1,2-thiazetidine 1,1-Dioxide, Synthesis and Reactions with C-Nucleophiles
✍ Schwenkkraus, Peter ;Merkle, Stefan ;Otto, Hans-Hartwig 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 670 KB

## Abstract __N__‐Silylated 3‐acetoxy‐1,2‐thiazetidine 1,1‐dioxide (5) is prepared from L‐cystine. Reactions of 5 with silyl enol ethers yield C‐3‐substituted β‐sultams 6, 12 and 15. Desilylation of 6 affords 7, which undergoes photochemical cyclization to give the bicyclic β‐sultam 10. In the cour

Properties and Reactions of Substituted
Properties and Reactions of Substituted 1,2-Thiazetidine 1,1-Dioxides: Functionalization and Reactions at C(4) of the β-Sultam
✍ Herbert Plagge; Nico Manicone; Hans-Hartwig Otto 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 248 KB

## Abstract The introduction of functional groups at the 4‐position of the __β__‐sultam ring was realized by the synthesis of mono‐ and disubstituted derivatives by reactions of __N__‐silylated __β__‐sultams with electrophiles in the presence of BuLi or LDA. As electrophiles, ketones, chlorosilanes