Direct synthesis of Fmoc protected amino acid hydroxamates from acid chlorides mediated by magnesium oxide
✍ Scribed by Ganga-Ramu Vasanthakumar; Vommina V. Suresh Babu
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 119 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The synthesis of Fmoc protected amino acid hydroxamates using Fmoc-amino acid chlorides and magnesium oxide is described. The method is simple and efficient, results in complete conversion, and gives good yields and satisfactory purity.
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## Abstract The successful application of the __Arndt‐Eistert__ protocol starting from commercially available __N__‐{[(9__H__‐fluoren‐9‐yl)methoxy]carbonyl}‐protected (Fmoc) α‐amino acids leading to enantiomerically pure __N__‐Fmoc‐protected β‐amino acids in only two steps and with high yield is re
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v