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Direct synthesis of Fmoc protected amino acid hydroxamates from acid chlorides mediated by magnesium oxide

✍ Scribed by Ganga-Ramu Vasanthakumar; Vommina V. Suresh Babu


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
119 KB
Volume
44
Category
Article
ISSN
0040-4039

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✦ Synopsis


The synthesis of Fmoc protected amino acid hydroxamates using Fmoc-amino acid chlorides and magnesium oxide is described. The method is simple and efficient, results in complete conversion, and gives good yields and satisfactory purity.


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