Direct synthesis of 3-(diaminomethylidene)chromane-2,4-diones from 3-formylchromones and hydroxylamine
✍ Scribed by V. Ya. Sosnovskikh; V. S. Moshkin
- Book ID
- 106521653
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 233 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1573-9171
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A reinvestigation of the reactions of 3-substituted chromones with hydroxylamine. Unexpected synthesis of 3-amino-4H-chromeno[3,4-d]isoxazol-4-one and 3-(diaminomethylene)chroman-2,4-dione
## Abstract The __Michael__‐type addition of a 4‐hydroxycoumarin (=4‐hydroxy‐2__H__‐1‐benzopyran‐2‐one) **1** to a __β__‐nitrostyrene (=(2‐nitroethenyl)benzene) **2** in the presence of AcONH~4~ leads to substituted (3__E__)‐3‐[amino(aryl)methylidene]chroman‐2,4‐diones (=(3__E__)‐3‐[amino(aryl)meth
## Abstract Michael‐type addition of hydroxycoumarins (I) towards β‐nitrostyrenes (II) in the presence of ammonium acetate provides access to title amino(aryl)methylenechromanediones (III) in high yields.