Direct Synthesis of 1,3-Diketones by Rh-Catalyzed Reductive α-Acylation of Enones
✍ Scribed by Sato, Kazuyuki; Yamazoe, Satoshi; Yamamoto, Rie; Ohata, Shizuka; Tarui, Atsushi; Omote, Masaaki; Kumadaki, Itsumaro; Ando, Akira
- Book ID
- 118010837
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 100 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1523-7060
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
The first example of N-heterocyclic carbene (NHC)-promoted intermolecular acylation of a-haloketones with aldehydes and a,b-unsaturated aldehydes (enals) is reported. The protocol involves carbonyl umpolung reactivity of aldehydes and enals in which the carbonyl carbon attacks nucleophilically on el