๐”– Bobbio Scriptorium
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Direct resorption of bone by human breast cancer cells in vitro

โœ Scribed by EILON, GABRIEL; MUNDY, GREGORY R.

Book ID
109711596
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
390 KB
Volume
276
Category
Article
ISSN
0028-0836

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โœ Kazuo Ohishi; Naoya Fujita; Yoshihiro Morinaga; Takashi Tsuruo ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer ๐ŸŒ English โš– 826 KB

Bone is one of the most common sites of metastasis in breast cancer. For metastasis to occur in bone, tumor cells must induce osteolysis by osteoclasts. Degradation of the osteoid layer by type I collagenase is a necessary process before osteolysis can occur because the osteoid layer hinders osteocl