Direct Repair of the Exocyclic DNA Adduct 1,N 6 -Ethenoadenine by the DNA Repair AlkB Proteins
β Scribed by Mishina, Yukiko; Yang, Cai-Guang; He, Chuan
- Book ID
- 120501056
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 48 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract O^6^βmethylguanineβDNA methyltransferase (MGMT) is a repair protein that specifically removes promutagenic alkyl groups from the O^6^ position of guanine in DNA. __MGMT__ is transcriptionally silenced by promoter hypermethylation in several human cancers. Methylationβspecific PCR (MSP)
## Abstract The localization of proteins to specific subcellular compartments often reveals clues regarding their biological functions. Although significant progress has been made towards understanding how damaged DNA is repaired, experiments to date have primarily focused on signal transduction pa