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Direct processing and presentation of antigen from malaria sporozoites by professional antigen-presenting cells in the induction of CD8+ T-cell responses

✍ Scribed by Plebanski, Magdalena; Hannan, Carolyn M; Behboudi, Shahriar; Flanagan, Katie L; Apostolopoulos, Vasso; Sinden, Robert E; Hill, Adrian VS


Book ID
108944495
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
226 KB
Volume
83
Category
Article
ISSN
0818-9641

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## Abstract The requirements for the conversion of CD8^+^ memory T cells into effector class I major histocompatibility complex (MHC) K^d^βˆ’restricted cytotoxic T (T~c~) cells __in vitro__ have been studied. Purified CD8^+^splenocytes from influenza A/WSN‐primed BALB/c (H‐2^d^) mice stimulated with