Direct preparation of vinyl halides from the corresponding ketones and acetyl halides
✍ Scribed by Khadija Moughamir; Bouchra Mezgueldi; Aziz Atmani; Hélène Mestdagh; Christian Rolando
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 178 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Vinyl chlorides and bromides are obtained in good yield from the corresponding ketones and acetyl halides in the presence of trifluoroacetic or trifluoromethanesulfonic acid. The Z isomer is selectively formed.
📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
A simple and efficient procedure has been developed for the synthesis of aryl-substituted chloro and bromo olefins from aromatic ketones and acetyl halides in the presence of silica gel-supported zinc halides. The Z-isomer is selectively formed.
The reaction of sodium diisopropyl phosphite with p-nitrobenzvl bromide was studied in detail by ( 1 ) isolation and identification of all products and (2) studying the effects of radical traps, such as dicycbhexylphosphine, di-tert-butylnitroxide, and the diisopropyl phosphite anion, on product dis