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Direct oxidation of boronates by peroxynitrite: Mechanism and implications in fluorescence imaging of peroxynitrite

✍ Scribed by Adam Sikora; Jacek Zielonka; Marcos Lopez; Joy Joseph; B. Kalyanaraman

Book ID
113630956
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
308 KB
Volume
47
Category
Article
ISSN
0891-5849

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Evidence shows that Na(+)/K(+)-ATPase from kidney, brain and liver is inhibited by nitric oxide (NO) and peroxynitrite anion (ONO(2) (-)), but the mechanism is unknown. The aim of the present work was to study the inhibitory effect of NO and ONO(2) (-) on erythrocyte Na(+)/K(+)-ATPase. Erythrocyte m