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Direct, One-Step Synthesis of Condensed Heterocycles: A Palladium-Catalyzed Coupling Approach.

✍ Scribed by Farnaz Jafarpour; Mark Lautens


Publisher
John Wiley and Sons
Year
2006
Weight
24 KB
Volume
37
Category
Article
ISSN
0931-7597

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A Two-Step Palladium-Catalyzed Coupling
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This work describes a Pd-catalyzed coupling of ferrocene al-derivative 10) and of course amides. A minor by-product of the coupling reaction, namely the homo-dimer bis(ferrocene kyne derivatives to iodo amino acids. Ferrocene carboxylic acid propargyl amides were easily obtained in high yield. carbo