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Direct Observation of the Multistep Helix Formation of Poly- l -glutamic Acids

โœ Scribed by Kimura, Tetsunari; Takahashi, Satoshi; Akiyama, Shuji; Uzawa, Takanori; Ishimori, Koichiro; Morishima, Isao


Book ID
127061594
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
48 KB
Volume
124
Category
Article
ISSN
0002-7863

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Helix-coil transition of poly(L-glutamic
โœ John B. Harry; James S. Franzen ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 958 KB

The folding of randomly coiled poly(bg1utamic acid) to the helical state has been studied in N-methylacetamide by titration methods. Since this solvent would be expected to form amide-peptide group hydrogen bonds with the unfolded form of the polymer, to a first approximation no helix stabilization