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Direct observation of mammalian cell growth and size regulation

✍ Scribed by Son, Sungmin; Tzur, Amit; Weng, Yaochung; Jorgensen, Paul; Kim, Jisoo; Kirschner, Marc W; Manalis, Scott R


Book ID
115454736
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
397 KB
Volume
9
Category
Article
ISSN
1552-4450

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## Background Conlon and Raff propose that mammalian cells grow linearly during the division cycle. According to Conlon and Raff, cells growing linearly do not need a size checkpoint to maintain a constant distribution of cell sizes. If there is no cell-size-control system, then exponential growth