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Direct modulation of insulin receptor protein tyrosine kinase by vanadate and anti-insulin receptor monoclonal antibodies

โœ Scribed by Roberto Gherzi; Cinzia Caratti; Gabriella Andraghetti; Stefano Bertolini; Antonio Montemurro; Giorgio Sesti; Renzo Cordera


Book ID
117058023
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
571 KB
Volume
152
Category
Article
ISSN
0006-291X

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โœ Chin K. Sung ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 677 KB

Although there is general agreement that insulin receptor tyrosine kinase activity mediates many of the actions of insulin, two types of studies suggest that non-tyrosine kinase dependent pathways may also exist. First, both monoclonal and polyclonal antibodies to the receptor have been shown to med