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Direct modulation of 25-hydroxyvitamin D3 hydroxylation in kidney tubules by 1,25-dihydroxyvitamin D3

✍ Scribed by J.L. Omdahl; L.A. Hunsaker

Book ID
118312791
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
344 KB
Volume
81
Category
Article
ISSN
0006-291X

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## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu